/Tag: skin barrier

4 Active: RENOVAGE™ For Cell Longevity

By |2016-12-06T13:24:12+00:00November 9th, 2016|FaceWorkshops, Facial Ageing, Product Reviews, Skin Concerns|

"We assess facial appearance as a whole; unconsciously adding-up visible signs of ageing. Restoring a youthful appearance means reducing the appearance of multiple parameters - lines and wrinkles, sagging [loss of tone], pigmentation, redness, dry skin, dilated pores, and the irregularities of the skin surface. All of the ageing signs are related to less efficient cell physiology; a skin composed of "ageing cells" enters the senescence phase more rapidly than necessary. It's due to a successive accumulation of DNA damage over time; less effectively repaired and less well protected DNA." Prolonging Cell Longevity. Renovage™ - geranylgeranone, is a high-tech global anti-ageing ingredient that acts on the four dimensions of skin ageing: surface, depth and time. It provides anti-ageing and protective effects against stress related damage by maintaining cell division [telomere stabilization and DNA maintenance], improving tissue quality [by optimal cell communication and rebalancing cell metabolism]. Renovage™ prolongs cell lifespan extension by one third. Clinical & Cell Culture Results. RENOVAGE™ acts as a cell facilitator and corrector. In vitro studies show several properties that aid recovery of skin function and structure to avoid premature entry into cell senescence. Protection and repair of oxidative lesions and nucleic elements  Keeping of catalasic antioxidant protection to 100% Reduction of apoptosis after UVB radiation exposure Reduction in the expression of heat shock proteins HSP27 and HSP70 The entry in senescence of fibroblasts is

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Skin Sensation & Sebum Profiling

By |2016-11-30T08:57:13+00:00August 19th, 2016|FaceWorkshops|

Market research experts ask frequently "What sensations do consumers look for in a moisturiser and why?".. What "feels good" to a consumer is driven by biology. Skin feel of a moisturiser depends on skin type - yet skin type is subjective to a consumer. Oily skin types find most moisturisers to "feel heavy or sticky", whilst mature and dry skin types cannot "find rich enough" moisturiser on the market. Sebum production seems to define the dry to oily spectrum at large - yet point-of-care sebum quantification & profiling have not been given enough of attention to date.  Sebum, hydration and skin barrier function differ, depending on ethnic group and age. It is both the amount of sebum as well as its content that affect skin condition [and facilitate skin feel]. US AFRICAN AMERICANS. African American women produce more sebum than Caucasian women. When looking at the sebum profile, wax esters are the class of lipids significantly higher in African American women [non polar, long, highly hydrophobic molecules that act as a barrier against excessive hydration or dehydration]. This correlates with better skin hydration, barrier function and probably also "oilier skin feel" in this ethnic group. BRITISH CAUCASIANS. Sebum has a moisturizing or conditioning effect on any skin type. In general, oilier skin types seem to have better skin barrier

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Higher BMI Health & Facial Ageing

By |2016-12-07T09:53:37+00:00November 26th, 2015|Facial Ageing, Skin Concerns|

Medical students are taught that half of the facts they learn are not true - we just don't know which half. Some of our most widely believed medical facts are based on almost no evidence at all. Is being slightly overweight (with BMI 25 - 30) healthier? Health weight range is not based on solid evidence (e.g. a significant study undertaken on many thousands of people or several such studies) with clearly defined basic categories i.e. BMI greater than 30 [Body mass Index; the ratio of body weight to the square of body height (kg/m2)]. Meta-analysis, is usually the holy grain of medical research, to provide the definitive answer to a scientific question. When the WHO (World Health Organisation) experts gathered to define obesity, BMI 30 has been chosen arbitrarily. Yet, obesity in middle age can reduce the risk of a person developing dementia later in life; to be overweight may well be healthier than to have normal weight. People who are considered overweight, with BMI 25 - 30, live longer. If methods of defining cut-off points in healthcare are largely arbitrary, it come as no surprise when the health definitions do not stand up to scrutiny.* In the ageing face, intuitively extra weight seems to add plumpness to the facial structures temporarily but research shows that thicker subcutaneous fat layer is

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